TEXTBOOK:  Fersht, A. STRUCTURE and MECHANISM in PROTEIN SCIENCE (1999) W. H. Freeman and Company, New York, ISBN 0-7167-3268-8 

OBJECTIVES:  This course is directed toward providing the student with a working knowledge of enzymes.  Topics will include a discussion of the tools used by the enzymologist, theory on catalysis, and a consideration of the mechanisms of specific enzyme-catalyzed reactions.

It is assumed that all students have a fundamental background in Biochemistry, and if not, the text by Voet and Voet published by John Wiley & Sons, Inc. should provide the necessary background.  Students should try to be conversant with lecture topics at the Voet and Voet level prior to lecture.  Additional reading assignments from the literature will be required.